90 research outputs found
Recommendations for ICT use in Alzheimer's Disease assessment: Monaco CTAD expert meeting
International audienceAlzheimer disease (AD) and other related dementia represent a major challenge for health care systems within the aging population. It is therefore important to develop better instruments for assessing disease severity and disease progression to optimize patient's care and support to care provide rs, and also provide better tools for clinical research. In this area, Information and Communication Technologies (ICT) are of particular interest. Such techniques enable accurate and standardized assessments of patients' performance and actions in real time and real life situations. The aim of this article is to provide basic recommendation concerning the development and the use of ICT for Alzheimer's disease and related disorders. During he ICT and Mental Health workshop (CTAD meeting held in Monaco on the 30th October 2012) an expert panel was set up to prepare the first recommendations for the use of ICT in dementia research. The expert panel included geriatrician, epidemiologist, neurologist, psychiatrist, psychologist, ICT engineers, representatives from the industry and patient association. The recommendations are divided into three sections corresponding to 1/ the clinical targets of interest for the use of ICT, 2/ the cond itions, the type of sensors and the outputs (scores) that could be used and obtained, 3/ finally the last section concerns specifically the use of ICT within clinical trials
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
BACKGROUND. Type 1 diabetes (T1D) results from destruction of pancreatic ÎČ cells by autoreactive effector T cells. We hypothesized that the immunomodulatory drug alefacept would result in targeted quantitative and qualitative changes in effector T cells and prolonged preservation of endogenous insulin secretion by the remaining ÎČ cells in patients with newly diagnosed T1D
Nouveaux concepts de consultations médicales en oncologie
International audienceDe nouveaux concepts de consultations sont actuellement en train de profondĂ©ment changer la façon dâexercer la mĂ©decine. Lâutilisation de questionnaires standardisĂ©s, des questionnaires patients (PRO, patient-reported outcome, et son application informatique, ePRO) ont dĂ©jĂ fait irruption dans nos consultations. En parallĂšle, la tĂ©lĂ©mĂ©decine, voire lâutilisation dâagents conversationnels automatiques mĂ©dicaux, permettent dâassurer une consultation Ă distance, plus accessible. Ces diffĂ©rents outils ont un intĂ©rĂȘt majeur en oncologie, notamment dans le contexte de la chronicisation des maladies et du suivi Ă long terme que les oncologues radiothĂ©rapeutes prennent en charge. Dans cet article, nous dĂ©taillons chacun de ces nouveaux concept
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